Sentence examples for deviation of the immune from inspiring English sources

Conclusion MiR-21 deficiency induced a deviation of the immune response towards a pro-inflammatory profile and increased mortality during experimental shock septic.

This suggests that the increased E2 concentrations during the luteal phase play a role in the deviation of the immune response towards a Th2-type response.

Lipoproteins are potent agonists of TLR2, which upon long term stimulation has been associated with the downregulation or deviation of the immune response.

The initial hypothesis of Th1/Th2 dichotomy postulated a deviation of the immune system towards a primarily Th1 (autoimmune) or Th2 (allergic) response, as demonstrated by the tendency towards one or the other type of disease in patient groups.

Therefore it is hypothesised, that in the era of antiretroviral therapy the incidence of anogenital cancer in HIV-positive patients will increase as consequence of prolonging survival combined with persistent deviations of the immune system.

3 Food allergy is one of the earliest manifestations of the immune deviation, 8 but also strongly coassociates with eczema in infancy and asthma later in life.

In addition, our data show that silibinin treatment results in deviation of macrophages immune polarization to a M1 phenotype in the tumor microenvironment.

The mean ratio of IFN-γ and IL-10 secreted in recall response to Bhsp65 by Celastrus-fed rats (ratio 8.79) was significantly lower than that of the water-fed rats (ratio 20.76), demonstrating that Celastrus preferentially facilitated the secretion of IL-10 and, thereby, induced a relative skewing (immune deviation) of the cytokine response towards a predominantly anti-inflammatory type.

AA is driven by pro-inflammatory cytokines (IFN-γ and tumor necrosis factor-α); in this context, Celastrus treatment facilitated the secretion of the anti-inflammatory cytokine IL-10 over the pro-inflammatory cytokine IFN-γ, resulting in the overall skewing (immune deviation) of the cytokine response to an anti-inflammatory type [ 26].

The calculation of the immune response index was based on the standard deviation because the healthy control data were considered to reflect a normal distribution.

Treatment with GAD65 seemed to induce a deviation of the GAD65-specific T-cell response toward a protective immune profile.