Your English writing platform
Free sign upExact(3)
The standard deviation of coverage depth for 454, GAIIx, and SOLiD was 25.5, 400.7 and 426.4, respectively.
Briefly, the median and median absolute deviation of coverage per exon of all reference samples, normalized on the total number of reads per sample, was calculated to determine the coverage distribution.
For the BM panel, with a 5-fold coverage the standard deviation of coverage values across unamplified BL and SCL samples was σ = 0.013 and σ = 0.036, respectively, suggesting little effect of input quantity.
Similar(57)
Finally, we generate random samples to achieve a pre-determined mean and standard deviation (SD) of coverage.
To allow quantitative comparison, this 'shortfall' difference is scaled by the standard deviation of the coverage probability distribution as given by Wendl [ 18].
This also ensured that standard deviations of the coverage of the confidence interval and the empirical power not exceed 1.6%.
On each chromosome, the standard deviation of relative reads coverage among the 150 samples was significantly correlated with the numbers of tags (Additional file 6: Figure S6).
We then computed the mean and standard deviation of the normalized coverage in the germline DNA for each patient at each gene.
We isolated 150 plasma samples with euploid fetuses to inspect the relationship between the tags number (unique reads) and the standard deviation of relative reads coverage.
Adjusted risk ratios (RRs) per standard deviation of tree canopy coverage were 1.17 for asthma (95% CI: 1.02, 1.33), 1.20 for any specific allergic sensitization (95% CI: 1.05, 1.37), and 1.43 for tree pollen allergic sensitization (95% CI: 1.19, 1.72).
As described by Li et al. [ 35], we calculated standard deviations of log ratios of coverage for a test and reference sample for bins (200 exons) of regions with similar coverage.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com