In this context it is particularly important to define and identify the 'healthy phenotype' as well as detect early deviations from this state, in order to permit intervention when a condition is still reversible.
High abundances of particular REP classes appeared to depend on the presence of the cognate RAYT gene, and deviations from this state could be attributed to recent or ancient mutations of rayt-flanking REPs, or RAYT loss.
To quantify the deviation from this baseline state, the difference in the distribution at any future time t and the control state is evaluated.
And if gold, perchance, did not quite achieve this ideal of a "stable unit of account," maybe its deviation from that state of perfection was minor enough that it didn't really matter much.
Next, following Gibbons et al., we used mixed-effects Poisson regression [ 24] and state-level control variables to decompose the overall unemployment rate effects into between-state (state mean unemployment rate) and within-state (monthly deviation from the state mean unemployment rate) effects [ 25] while conditioning on common factors affecting prescribing behavior.
We consider that the adopted steady state for this period is satisfactory for emphasizing the results, because the previous 2001 2005 slow slip and the current slow slip were clearly detected as a deviation from this adopted steady state.
Furthermore, we consider that the steady state for the period of this study is effective for emphasizing the results because the Bungo, northern Miyazaki, and southern Miyazaki slow slips clearly appeared as deviations from this steady state.
Newton's first law, for example, established his physical system upon the tendency of a body in motion to persist either at rest or in uniform motion in a straight line, requiring a causal explanation for any deviations from this initial state.
