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Treating perfect periodicity as a model, whose fit to (or deviation from) the sequence data of interest is to be measured, a chi-squared test can be developed.
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In 1 of these sequence sections, we found a deviation from the reference sequence used (Y. pestis strain CO92 plasmid sequence AL109969.1).
This is because there are an increasing number of possible sequences as the deviation from the consensus sequence increases, and so the null hypothesis that similarity to the consensus sequence arose by chance (as opposed to natural selection) becomes more credible.
Since LINE-1 sequences are highly variable, we found that the longer the distance to the sequence start the greater the deviation from the consensus sequence and the less accurate the reflection on the actual real methylation levels.
The sensitivity is defined as the number of sites in which both sequencing and microarrays detected a deviation from the reference sequence divided by the number of sites where a variant was detected by using the microarrays.
In cases where a deviation from the reference sequence was observed, it was confirmed through re-sequencing from the opposite direction.
The miRNA sequences detected in these studies also show significant deviation from the reference sequence deposited in miRBase.
The superior predictive power of ncIDP-assign translates into detection sensitivity of chemical shift deviations from the sequence-specific 'random-coil' values due to resonance misassignment.
If the GeneBASE-xhyb estimates are no more concordant with sequencing estimates than the GeneBASE estimates, then we would expect T to be centered at 0. If GeneBASE-xhyb tends to show smaller deviations from the sequencing estimates than GeneBASE, then we expect T to be shifted to the right.
This n499g was located in segment 1 and obviously is not a deviation from the reference sequence.
Mutation type describes the deviation from the reference sequence leading to the change in the DNA.
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