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This pathway may even eliminate deviant tumor cells generated by inactivating mutations of tumor suppressor genes [ 113, 114].
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The feature of self-renewal in stem cells is shared with tumor cells, and deviant function of the stem cell regulatory networks may, in complex ways, contribute to malignant transformation and the establishment of a cancer stem cell-like phenotype.
These drugs aim, so far with modest success, to block aberrant molecules in tumor cells while leaving normal cells unscathed.
Other research involves the tumor cells themselves.
The healthy cells around the tumor cells, which don't express the tumor gene, are untouched.
He then administered live tumor cells to both.
Chemotherapy and radiation are efficient killers of tumor cells.
So interfering with the proteasome could kill tumor cells.
Tumor cells, like bacteria, can develop resistance to drugs.
Some experts believe that drugs that kill most tumor cells do not affect cancer stem cells, which can regenerate the tumor.
The study fused blood cells called dendritic cells with tumor cells from each patient, then injected the hybrid cells back into the patient.
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