The feature of self-renewal in stem cells is shared with tumor cells, and deviant function of the stem cell regulatory networks may, in complex ways, contribute to malignant transformation and the establishment of a cancer stem cell-like phenotype.
The study findings offer insight into new mutations likely to resist treatments based on the degree that specific mutations drive the growth and evolution of cancer, and the potential of therapeutic that may be able to stop deviant gene function.
Deviant cerebellar functioning could explain the lower performance of FMRP mouse mutants and patients with FRAXA in the short-term acquisition of the delay conditioned eyeblink response (Koekkoek et al. 2005).
At the same time, the landmark Danish adopted away studies of schizophrenia conducted by Rosenthal and coworkers [ 4] determined that relatives of patients with schizophrenia displayed deviant psychological functioning, but not all signs of schizophrenia, providing further evidence for a spectrum of schizophrenia-related disorders.
15 In the Hempel assessment, five domains of function are assessed as typical or deviant: fine motor function, gross motor function, posture and muscle tone, reflexes and visuomotor function.
In the "oddball" sequence "day1" serves as a deviant and "deh1" functions as a standard.
Second, to investigate nonlinear and hemodynamic effects, the contrasts entered into a mixed-model analysis of variance with deviant type and basis functions (HRF and TD) defined as within-subject factor and age-group defined as between-subjects factor.
Figure 2 compares mean LDN and MMN amplitudes collapsed across the six electrodes for the two groups as a function of deviant.
Figure 5 displays the average delta BOLD for each condition ("oddball"/"control") and hemisphere (left/right) as a function of deviant stimulus and ROI.
Besides recall biases, parents' reports may be prejudiced by their own norms and attitudes regarding normal and deviant (social) behaviors and functioning.
