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Significant ERP differences between the standard and deviant conditions were found in 8 out of 10 adult subjects already in 80 ms and prevailingly in interval 145 260 ms from the initial stimulus presentation.
This conceptual distance manipulation defined 5 deviant conditions.
When combined, the 2 types of conceptual tuning permit discrimination between all the adjacent deviant conditions.
The calculated distances (D) between the anchor and deviant images used in our experiment are shown in Figure 2 C for the different deviant conditions (Levels 1 5).
Previous studies have assumed that significant variation observed among deviant conditions (i.e., recovery) necessarily indicates that adaptation effects have occurred in the same voxels.
In order to exclude the possibility that the laterality of the MMNm originated from the sound stimulus itself, we counter-balanced total auditory inputs identical between spectral and temporal deviant conditions.
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As a first step to determine the range, the difference between the deviant and the standard (deviant condition minus standard condition) was calculated.
Mean amplitude values (instead of peak amplitudes) also prevent possible biases arising from the difference between trial numbers in the standard and in the deviant condition, meanwhile keeping statistical power (Luck, 2014).
Furthermore, in order to make sure that differences between the conditions are not due to the possibly larger variability in the Number deviant trials compared to the Shape deviant trials, the Bartlett's test for equal variance was performed for each deviant condition.
It is difficult to visualize patterns that occur in 5 dimensions (defined by the 5 beta weights in each voxel to the different deviant level conditions).
However, the inconsistent detection of some targets, as in the case of histones proteins (H2A), could be attributed to a biological variability, possibly associated with deviant physiological conditions.
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