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Unless the concentrations of mineral ions such as sodium, crystalloids such as glucose, and wastes such as urea are maintained within narrow normal limits, bodily malfunction rapidly develops leading to sickness or death.
While this is mostly asymptomatic, it can be a cause of (referred) pain when pseudoarthrosis develops leading to accelerated degenerative disease.
With increasing cumulative dose, a chronic sensory neuropathy develops, leading to long-lasting functional disability [1], [4].
A vicious circle of continuous damage and inadequate repair develops, leading to disc degeneration rather than healing.
Our simulations correctly demonstrated that, once the ligands are removed from the ligand-bound structure, a substantial gap between the two subunits develops, leading to a reduced dimerization interface.
Participation in the study will cease if a major fetal anomaly is detected or serious illness develops leading to IUGR (birth weight below the 10th percentile of the recommended gender-specific birth weight for gestational age reference curves [ 16]); however, all mothers recruited will be followed-up until the end of the study for the purposes of describing the whole population.
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Only later during the middle of the Paleogene Period, about 40 million years ago did cooler, drier climates develop, leading to the development across large areas of other vegetation types.
High temperatures increase the rate at which mosquito larvae develop, leading to the rapid subsequent development of adult life forms of the mosquito.
[25] Furthermore, development of novel printing and coating processes have been developed leading to roll-to-roll processing of organic solar cells [32, 33, 34].
Afterward, a sort of receiving line developed leading to Mr. Geltman, with friends stopping to share a few words.
A good diet enables a child's brains and muscles to better develop, leading to lifelong benefits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com