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Calibration (i.e., how well predicted probabilities agree with actual observed risk) was measured by the Hosmer Lemeshow statistic (goodness-of-fit test and calibration curves) that compares the average predicted risk within subgroups to the proportion that actually develops disease.
Differences in immune response genes are believed to be important in determining whether an individual successfully contains the infection or develops disease [3], [4], [5], but the genes responsible remain largely unknown.
The probability that an adult individual with epigenotype ij develops disease in environment u is given as α u, ij.
Whether the host can control the infection or develops disease depends on the complex interaction between parasite and host.
When the average predicted risk matches the proportion that actually develops disease within subgroups of a prospective cohort, the model is considered well-calibrated.
When the average predicted risk within subgroups of a prospective cohort matches the proportion that actually develops disease, the model is considered well-calibrated.
Similar(47)
In summary, we demonstrate that a subset of patients with multiple sclerosis develops disease-associated demyelinating and axopathic autoantibody responses that target antigens expressed by highly differentiated myelinating oligodendrocytes.
The mice injected with the short nanotubes or small carbon clumps did not develop disease.
Data showed that people who migrated from regions of lower cancer risk to those with higher cancer risk soon developed disease at rates consistent with their new environment.
But they did not develop disease symptoms.
Remineralization treatment can stop the process of developing disease.
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CEO of Professional Science Editing for Scientists @ prosciediting.com