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Yet despite of new developments, therapeutic options are still rare and prognosis of patients in advanced stages remains poor [ 24].
We correlated clinical developments, therapeutic interventions and causes of death in 2 periods: 1987-1993 and 2009-2013.
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Despite considerable advances in our understanding of the pathophysiology of brain damage during development, therapeutic options are still extremely limited.
In areas of new drug development, therapeutic assessment, and disease pathogenesis studies, this technique has already shown great advantages.
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Numerous growth factors account for tissue and organ development and therapeutic efficiency.
The exploitation of small molecule Wnt inhibitors would facilitate the development of therapeutic reagents.
& Takahashi, J. S. Development and therapeutic potential of small-molecule modulators of circadian systems.
The approach has become a key element in the development of therapeutic drugs, particularly for cancer.
The combined status of ATM and p53 link tumor development with therapeutic response.
Friedman, S. L., Neuschwander-Tetri, B. A., Rinella, M. & Sanyal, A. J. Mechanisms of NAFLD development and therapeutic strategies.
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