From the pseudoglandular to the canalicular stage of lung development, the appearance of primary and secondary crests marks an essential step in lung growth.
In three different experimental paradigms (orthotopic tumor cell line allografts, tumor transplantation, and de novo tumor development), the appearance of detectable MMTV-PyMT mammary tumors is significantly delayed in the NG2 null mouse.
Up until the turn of the century, most of the age-grading methods for insects were based on changes in the reproductive system, such as the changes in follicular development, the appearance of the male and female reproductive tract, as well as the accumulation of follicular relics (Hayes and Wall 1999).
The arbitrary nature of the orientation of stripes found in adults indicates that during normal development the appearance of iridophores at the horizontal myoseptum serves as a morphological landmark for stripe orientation, but subsequent stripe formation as well as stripe width are determined in an autonomous manner.
It is mostly undisputed that pre-human australopithecines did not have communication systems significantly different from those found in great apes in general, but scholarly opinions vary as to the developments since the appearance of the genus Homo some 2.5 million years ago.
In A. thaliana, mutation of the DGAT1 gene severely affects seed development, causing the appearance of wrinkled and incompletely filled seeds, aberrant seedling growth, reduced seed oil content, an increased DAG/TAG ratio and the beta-oxidation of elevated fatty acid (FA) levels [ 13, 15].
Early suburban development gave the appearance of a wagon wheel.
An independent, reinforcing, and almost simultaneous development was the appearance of the English longbow as the premier missile weapon of western Europe.
The most surprising development is the appearance of actual romantic chemistry where Lady Mary is concerned – a no-show during the entire three seasons of her "love affair" with Matthew.
Web hardware: One very interesting development is the appearance of dedicated web server devices.
