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Although our application of the GRADE system may have implications for the validity of our final recommendations, it can be argued that our approach was in fact an improvement on previous exercises in national guideline development that lacked transparency [ 45].
Musashi-1 is a protein that binds to molecules of RNA and helps to promote cell growth during development: mice that lack this protein have serious brain defects and die shortly after birth.
We have recently shown that DAG1 is expressed during embryo development, and that lack of DAG1 affects this process [ 24].
Or it was created by a development team that lacked real engineering or architecture experience and needed to save money on the project.
The finding could eventually guide drug development for cancers that lack effective treatment.
Researchers knew that reelin plays an important role in brain development because mice that lack the reelin gene have a misshapen cerebral cortex and a peculiar gait (thus the nickname "reeler" mice).
The ban can be seen as an application of the "precautionary principle", established at the 1992 Rio Conference on the Environment and Development, which advocates that "lack of full scientific certainty shall not be used as a reason for postponing cost-effective measures to prevent environmental degradation".
Now, with the development of mice that lack the specific STAT proteins, we can begin to dissect the specific roles of the STATs in breast cancer pathogenesis.
By studying non-peptidergic nerve cell development in mice that lack NGF, Runx1 and other associated proteins, Huang et al. have now established the sequence of events that regulate the development of this nerve cell subtype.
Moreover, zygotic expression of wild-type Ph and Psc-Su z 2 Psc-Su z 2s unable to restore normal developroteins embryos that lack maternally deposised Ph and Psc-Sunableprotoins, restoreively (supplemenormalmaterial Fig. S2) (Smouse et al., 1988).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com