From this perspective, it is reasonable to hypothesize that extemporaneous exposure to estrogens or xenoestrogens during fetal development may alter the reciprocal interactions that induce and maintain tissue organization, and that these alterations in turn generate abnormal tissue structures and altered control of cell proliferation.
Without easements, scattered development may alter fire management on 12,370 ha (17.5% of undeveloped wildfire containment areas) by requiring more fire suppression and reducing options for prescribed burning.
In the present study, we hypothesized that the absence of direct contact with adults during development may alter not only song production (as already demonstrated [3] [6], [42]) but also the ability to categorize functional classes of songs (as reflected by differential responses to these songs, like those we observed in wild-caught adult male starlings [38]).
These results provide further evidence about the role of PTEN in the brain and suggest that manipulation of the PTEN/Akt signaling pathway during development may alter the basal state of dopaminergic neurotransmission and could provide a therapeutic strategy for the treatment of Parkinson's disease, and other neurodegenerative disorders.
Binding of PBDEs to thyroid hormone transporters and receptors during critical periods of brain development may alter the course of development toward an autistic phenotype (55).
Thus, the epigenetic deregulation of specific genes (eg, hormone receptors) during development may alter their expression or subsequent activity later in life, predisposing the organism to disease in adulthood.
Expected technological developments, however, may alter the projected rate of change.
Development project may alter existing physical and social situation of the concerned region and its surroundings that may bring unanticipated adverse impacts (Long et al. 2007; Madon 2000; Szirmai 2015) on society.
We propose that, during pituitary development, the 18q rearrangement may alter expression of 18q genes or of X chromosome genes that are translocated next to the HCNEs.
