These results suggest that additional genotypic changes are required for cancer development in this context.
A recent development in this context concerns two anti-EGFR antibodies, cetuximab and panitumumab, that have been labeled for use in metastatic colorectal cancer (CRC) under the condition that the tumor carries a wild-type KRAS gene [5], [6].
The term "development" in this context should be interpreted in a broad sense, referring to physical, mental, emotional, cognitive, social and cultural development.
Lastly, policy development in this context must be necessarily proactive and aimed primarily at maintaining public trust in and support for cell-based research and interventions.
Workforce development in this context includes the support required to equip those providing care to older people with the right skills, knowledge and behaviours to deliver safe and high-quality services.
By contrast, stochastic specification, implied by the last cell standing model, constrains the evolution of novelty in the early embryo because germ line development in this context requires a signalling niche provided by neighbouring somatic cells; perturbations to homeostatic signalling within this niche would divert PGCs to a somatic fate, terminating the germ line.
These differences in kinetics of colonization between different fetal thymi are likely to reflect the effects of genetic variation within the human population on fetal thymus development; in this context, it is well established that thymus organogenesis proceeds at different rates in different inbred mouse strains.
What we mean by personal development in this context can be interpreted with the help of according Dewey's theory regarding human nature and conduct [ 36] a human is seen as an experiential person who lives and acts and thereby develops in the interplay with other humans.
This survey discusses recent developments in the context of spherical designs and minimal energy point configurations on spheres.
This paper presents an open-source Eclipse-based framework which aims to facilitate the exploration and development processes in this context.
