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In the light of rapid developments in genomic technologies, medical genetics is shifting from the present "phenotype-first" medical model to a "data-first" model, which leads to multiple complexities.
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Recent developments in genomic technology, particularly high-throughput cDNA sequencing and development of expressed sequence microarrays, have made possible the profiling of global gene expression in experimental fish tissues.
Advances in genomic technologies have enabled development of many novel genome analysis methods that may have applications in the understanding, diagnosis, and management of genetic diseases and cancer.
Advances in genomic technologies with the development of high throughput sequencing methods will certainly improve the possibilities to access a more accurate molecular diagnosis and to go beyond the identification of validated targets as a large number of genes can be screened for actionable changes.
Recent advances in genomic technologies have allowed the development of new strategies for the molecular diagnostics of human diseases.
The use of these molecular approaches for biomarker development is still in its infancy but is now feasible with recent advances in genomic technologies.
Although investments in genomic technologies have increased in other regions of the world, scientists in low- to middle-income countries that could utilize these technologies to improve health and to promote equity are concerned that the commercial development of genomic technologies will widen the gap between the developed and the developing world [ 11].
Further developments in functional genomic technologies are beginning to unravel the contribution of individual genes to intrinsic aspects of tumour biology, such as metastatic potential, uncontrolled cell proliferation, cellular invasion, migration and drug resistance.
Advances in genomic technology have improved our understanding of the genetic events that parallel breast cancer development.
Recent advances in genomic technology have improved our understanding of the accumulation of genetic events that parallel breast cancer development; they have also revealed the complexity of premalignant lesions.
Since 2003 there has been rapid, revolutionary development of genomic technologies and extensive advances in knowledge of the impact of genomic variation on human disease.
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