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Here we present the first detailed analysis of locomotion patterns during developmentally relevant timescales, that is, periods in which significant developmental changes occur.
Summary: We present a method, LineageProgram, that uses the developmental lineage relationship of observed gene expression measurements to improve the learning of developmentally relevant cellular states and expression programs.
A genomewide survey of developmentally relevant genes in Ciona intestinalis.
Satou, Y. & Satoh, N. Genome wide surveys of developmentally relevant genes in Ciona intestinalis.
These results support the effectiveness of in vitro neural differentiation of human pluripotent stem cells in yielding developmentally relevant NPCs for studying neural malformation caused by ZIKV infection.
His studies on the corticospinal pathway, the principal motor system in primates, demonstrated that the application of developmentally relevant cues was insufficient for mediating regeneration of the corticospinal motor axons (Hollis et al. Exp Neurol 2009).
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Spatio-temporal expression trajectories (developmentally-relevant phenotypes) in ensembles of highly-modular (fully interconnected) networks exhibiting distinctive regulatory topologies, which are operative in the context of one-dimensional syncytial embryos, were simulated.
Most of these protocols have been developed based on our knowledge of developmentally-relevant signals identified in animal models.
Multicellular organisms present challenges to understanding developmentally-relevant transcriptional programs, as cell-specific differences in gene expression can be masked by expression in multiple cell types.
Variable-centred approaches examine statistical associations between measures of adversity, hypothesised resource factors, and developmentally-relevant functioning, using regression-based analyses.
Developmentally and culturally relevant materials should be made available in sufficient quantities to ensure quality learning.
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