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The Peak Day method is highly cost-effective and could be applied by researchers to target periconceptional or very early developmental stage exposure assessment.
Basic research in the toxicology of adolescence needs to take into account the appropriateness of animal models for this distinctive human developmental stage; risk assessment must take into account pharmacokinetic and lifestyle factors.
Tadpole developmental stage was assessed using Gosner nomenclature [42].
Note, however, that the NCD and noNCD groups are well matched in age, reducing the impact of developmental stage on group difference assessments.
Pregnancy at 14 d was confirmed by assessment of developmental stage of embryos at autopsy [ 40].
Waldman et al. (2010) found significantly greater correlations observed in adult tissues than the fetus, pointing to the importance of developmental stage in these kind of assessments (Waldman et al. 2010).
Thus, the cells used for these experiments were identified based on a visual assessment of larval developmental stage and when possible of partial capping of the cells.
Two prime issues for assessments of children are the developmental stage of the subjects and the most appropriate respondent for questionnaires.
7 Children younger than 9 months were not considered because at their developmental stage they cannot localise painful stimuli, a key criterion in our assessment of coma.
During the assessment of individual fractures, the site, fracture type, and developmental stage of the child can help to determine the likelihood of abuse.
Pain assessment requires an understanding of a patient's chronological age, developmental stage, functional status, cognitive ability, and emotional state [ 24].
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