Stem cells in one organ thus seem malleable enough to adopt a whole new developmental programme in another organ, even late in a person's life.More important, though, in Dr Barsky's opinion, is that the new data support the idea that tumours arise from stem cells that have gone wrong.
Ageing, he thought, comes about because this developmental programme, this constant change, never turns off.
Still, his fundamental idea of a developmental programme leading to ageing has persisted.
These environmental responses must intersect with the intrinsic developmental programme of the plant, which is responsible for the general formation and maintenance of the root system.
After fertilisation, sperm DNA exchanges protamines for histones recruited from oocyte cytoplasm, reconfiguring both parental genomes into an epigenetic state conducive to activating the embryonic developmental programme.
The presence of multicellular pollen in the in vitro system developed here indicated the switch of developmental programme which constitutes a crucial step in the design of protocols for the regeneration of microspore-derived embryos and plants.
These processes are governed by a precise developmental programme in response to stimuli from the host and the environment.
Generation of a functional nervous system is a result of a highly specific developmental programme of events.
In this compromised infant rats, leptin administration shifted the developmental programme from a metabolically unhealthy to a healthy one [47].
A key role for ladybird in leg myogenesis is further supported by its capacity to repress vestigial and to down-regulate the vestigial-governed flight muscle developmental programme.
Like Lbx1 in vertebrates, lb marks an entry point in the leg muscle developmental programme and specifies properties of myoblasts that give rise to appendicular muscles.
