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Rapid growth rates of head circumference and body size during infancy have been reported to predict developmental pathologies that emerge during childhood.
This is of special interest as many retinal degenerative diseases are not developmental pathologies.
Our case series supports each of these reported associations but none of these help in elucidating the underlying developmental pathologies.
However, not all developmental pathologies could be correlated with structural abnormalities in conventional MRI.
Cdk5 has been previously shown to be abnormally expressed in epilepsy-associated developmental pathologies such as focal cortical dysplasia (Sen et al., 2008).
Direct experimental evidence in vivo on endogenous gene regulation and development is required to unequivocally demonstrate a role for unliganded receptor in frogs and reveal potential developmental pathologies in the hypothyroid condition.
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Pediatric and Developmental Pathology 2018; Nov-Dec; 21 6):537-47.
Research in developmental pathology has stressed the biological importance of this other kind of cell death, which has been referred to as programmed cell death.
Dr. Vilches-Moure is a diplomate of the American College of Veterinary Pathologists, and his collaborative research interests include cardiac development and pathology, developmental pathology, and refinement of animal models in which to study early cancer detection techniques.
Since the targets and functions of most RBPs — in the heart and at large — are not fully understood, this review focuses on the expression and roles of RBPs that have been implicated in specific stages of heart development or developmental pathology.
By selecting for malfunctional fusion variants in yeast, they identified a Vip2 proenzyme with significantly reduced enzymatic activity and with the ability to be expressed as a transgene in corn plants without causing developmental pathology.
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