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The CBT manual under investigation, enhanced for early adolescents with ASD, yielded meaningful treatment effects on the primary outcome measure (PARS), although additional developmental modifications to the manual are likely warranted.
Ontogenetic changes (i.e., developmental modifications occurring during an organism's lifespan) can be more drastic than phylogenetic changes, perhaps due to the speed and scope with which development advances, and similarly reflect major biological processes.
Yes, it is always good to introduce the word 'evolution' to conversations about natural phenomena, but in a formal way, changes in the history of our (or another) planet or other heavenly body reflect developmental modifications of the same entity, rather than a newer offspring.
A detailed study of tooth morphology in mutants bearing losses of functions of these two genes thus appears necessary to test the pattern variability induced by the developmental modifications.
Although some developmental modifications occur, most can be attributed to growth (Ey et al. 2007), changes in hormone levels (Pfefferle et al. 2008) or arousal (Fichtel et al. 2001).
The different stem samples and developmental stages were chosen since previous studies [ 6, 50] have shown that the main developmental modifications associated with bast fiber formation and cell wall maturation occur in the apical and medium stem tissues between the vegetative and green capsule stages.
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In this study, we exposed embryonic medaka to TCDD to induce developmental modification(s) of both cartilage and bone formation.
We also included oligonucleotides for several ISG-like proteins, four of which, Tb927.5.310, Tb927.5.420, Tb927.5.430, and Tb927.5.630, are significantly upregulated in BSF, suggesting additional and so far uncharacterised developmental modification of the parasite surface.
Assuming that these single neuron modifications express a developmental adjustment, we next examined whether more aspects of neuronal activity have been modified leading to detectable behavioral changes.
Interestingly, M2 was enriched for terms associated with chromatin modification, suggesting a developmental alteration of epigenetic regulation.
A spectrum of developmental and behavioral modifications in adolescent, young-adult and aged animals resulted after prenatal nicotine exposure.
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