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Although the biochemical mechanisms of NMD have been studied intensively, its developmental functions and importance are less clear.
The Wnt pathway has previously been shown to be involved in many developmental functions, and it drives the renewal and proliferation of many types of stem cells.
Plug-ins are used for many different developmental functions and are shared among species.
Previous work with Ahr knock-out mice revealed the existence of dioxin-independent functions of Ahr, including developmental functions and ageing-related detoxification [1], [2], [3].
The data establish new roles for Wt-Ub and the UPP to execute these critical developmental functions and they allowed us to elucidate how denucleation is regulated.
In plants they regulate several developmental functions and play an important role in plant-microbe interactions.
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Altogether, our data suggest a considerable complexity in the composition, the developmental function and the tissue-specificity of the different C. elegans Mi-2 complexes.
Thyroid hormones are responsible for regulating metabolic and developmental function and are critical for normal foetal and neonatal development.
As the ICF version for children, (ICF-CY) [ 26] describes domains of developmental functioning and activities and environments relevant for children, for example family and school.
We investigated the origin of the Gal-1A/Gal-1B divergence to gain insight into when their developmental functions originated and how they could have contributed to vertebrate phenotypic evolution.
Although not fully elucidated, Lys catabolism apparently serves additional physiological and developmental functions in plants and animals [3] [5].
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