Exact(7)
Finally, we detected the full term developmental efficiency of CBHA treated and non-treated embryos.
In this study we use this HDACi to treat porcine nuclear transfer embryos to investigate whether it affects the developmental efficiency in pigs.
To assess the efficacy of human embryo twinning by blastomere biopsy at different early embryonic stages (splitting efficiency) and to determine the in vitro developmental capacity of twinned human embryos (developmental efficiency).
On the other hand, the developmental efficiency of markers and polymorphism of designed primers are comparatively low.
For example, when treated with histone deacetylase inhibitor TSA, embryos that have been generated by somatic cell nuclear transfer exhibit poor quality, despite high developmental efficiency [30].
It has been suggested that the commonly observed low developmental efficiency of NT embryos may not be largely due to nuclear reprogramming during early embryo development but potentially caused by abnormal gene reprogramming during postimplantation feto-placental development [ 20].
Similar(53)
The in vitro developmental efficiencies of embryos injected with Cas9 mRNA/sgRNA (∼79%) and embryos injected with water (∼77%) were both very high and comparable with each other, suggesting that the microinjection manipulation and the Cas9 mRNA/sgRNA had little effect on pig early embryonic development (Supplementary information, Table S1).
This study provides compelling evidence that individual growth- and developmental rate and efficiency can evolve over fewer than 22 generations under conditions widely theorized to impede local adaptation.
The patterns of differentiation in larval developmental rate and efficiency in relation to temperature in the Lesjaskogsvatnet grayling supports findings in a number of other studies; this include 1) the relationship between temperature environment and individual growth rate [ 32] and development rate [ 33, 34], and 2) trade-offs between muscle growth and skeletal differentiation [ 22, 35- 37].
A small body size can be achieved by reducing developmental time (keeping growth efficiency constant) or by reducing growth efficiency (keeping developmental time constant).
Results: A non-linear developmental change of VSWM efficiency was observed in the results from the ATMT-C.
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