We couldn't agree more, and applaud Watt's pioneering empirical studies that demonstrate how developmental processes construct fitness differences between genotypes (Watt 1985, 2000, 2003; see also Badyaev 2009).
In our articles we discussed cases like the repeated rapid adaptation of sticklebacks to post-glacial lakes through the loss of a pelvic girdle (Chan et al. 2010) and rapid adaptation and range expansion of the house finch in North America (Badyaev 2009), arguing that these examples, alongside many others, illustrate how developmental processes construct evolutionary pathways.
Cultured neurons present an opportunity to study the developmental processes that construct the nervous system.
Here, we investigate the transcriptomic alterations and splicing events during mouse lens formation using RNA-seq data from multiple developmental stages, and construct a molecular portrait of known and novel transcripts.
Because the developmental processes that construct cognitive mechanisms during an individual's lifetime will also have reproductive consequences for the organism, cognitive development will also be a target of natural selection.
However, using our normalized cDNA libraries for deep sequencing, we have enriched the porcine transcripts from different early developmental stages to construct the EMPV1 microarray platform.
As we extend these investigations to laminated 3D systems, a key question for these approaches is whether it is possible to exploit developmental biology to construct circuits that reflect those found in the developing human cortex in vivo, including canonical cortical microcolumn circuits.
1 Advanced mainly through work in developmental psychopathology, the construct of resilience has been explored in biological, psychosocial, genetic and neurobiological fields. 2 3 Resilience has been studied in the backdrop of protective and risk factors related to positive or negative psychological outcomes, and also on individual, social and ecological levels.
Current Research and Scholarly InterestsHow are genes regulated to construct a developmental program?
