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The combination of complete genomic sequence data, genetic tractability, and sophisticated analytical tools for D. melanogaster and P. fluorescens will facilitate future characterization of the cellular, molecular and developmental components of the host-microbe interactions observed in this study.
However, for most traits, it is difficult to predict genetic and developmental components of the selection process.
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Patients with severe SMA show symptoms shortly after birth, suggesting a potential developmental component of SMA pathogenesis.
A very important factor in the prevention of the developmental component of diabetes risk is the physiological state in which the parents enter pregnancy.
Severe type I-II SMA patients show symptoms during the newborn and early-infant periods, suggesting a potential developmental component of SMA pathogenesis.
A very important factor in the prevention of the developmental component of diabetes risk is the physiological state in which the parents enter pregnancy – i.e. the diet, body composition and lifestyle of the mother and to a lesser extent the father.
There is a lack of animal models of adult-onset SMA, and the post-developmental components of SMA pathogenesis remain elusive.
The mechanisms responsible for the establishment of nucleolar dominance are poorly understood but once established there is a developmental component to the maintenance of the silenced state.
For many traits, the relative importance of selective and developmental components remains understudied.
There is evidence for genetic and developmental components in USVs in rodents [35], [36], [37] and spectral components of USVs can change in captivity over several generations [38].
There seems to be both biological and developmental components.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com