Exact(10)
Throughout adult life, new developmental commitment of adult stem cells causes metaplastic conversions to occur frequently in some organs.
As leukocytes progress through hematopoiesis, their expression pattern of cell-surface and intracellular molecular signatures is reflective of the cells' stage in their developmental commitment program.
Instead, the Institute demonstrated financial and developmental commitment to women's ideas and careers.
It is not surprising that dynamic cell cell interactions are important in establishing the proheterocyst positions (developmental commitment [19]), because some competitive selection or lateral inhibition between cells is required [20], [21].
In any event, given the likelihood discussed above that many of the MAUD hits reveal differences in developmental commitment between neurons and glia, we expect that specific enrichment for genes showing monoallelic expression will be significantly larger than 8-fold in more homogeneous cell populations.
The RNA binding protein lin-28, a biomarker of undifferentiated ESCs, is a bona fide target for let-7 during developmental commitment [ 38, 39].
Similar(50)
Signal duration (e.g. the length of time over which a signaling intermediate is active) is a critical determinant in mediating cell decisions in numerous biological processes including cell growth, proliferation, and developmental lineage commitments (Fig. 1) [ 1- 8].
Signal duration (e.g. the time over which an active signaling intermediate persists) is a key regulator of biological decisions in myriad contexts such as cell growth, proliferation, and developmental lineage commitments.
E15 is the developmental stage when commitment to terminal differentiation occurs 16.
We predict gametocyte densities as functions of host or parasite factors at earlier time points, accounting for the developmental delay between commitment to gametocytogenesis and observation of mature gametocytes.
In our training for police officers at Strategies for Youth, a nonprofit organization dedicated to improving police-youth interactions, we start with the premise that effective policing requires developmental competence and a commitment to building a relationship that is fair, respectful and proportional to youths' actions.
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