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Regulators used to leave it up to issuers to decide whether a development was significant enough to merit disclosure in a filing.
The variation at EC50 concentration for cumulative time and effective development was significant (P < 0.05).
The variations observed between EC50 and control to increase in cumulative time and decrease in effective development was significant at P < 0.05.
BBC deputy political editor James Landale said the development was "significant" as it was the first time the prime minister had formally accepted any offer from the broadcasters on the debates.
Nevertheless, none of neuron development, NO signaling, or skeletal development was significant according to this analysis, with q-values of 0.365, 1, and 1, respectively.
This led for instance to the observation that the Biological GO-clusters "development" was significant under-represented for both ERK1 and ERK2 knockdown.
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This off-the-field development is significant because it could have ramifications on the field.
The development is significant, says Prof Richard Harvey, who has been working with Bear on the research.
They then unsuccessfully tried to sell it to Equity Office, a major national real estate investment trust, but the obstacles to development were significant.
Two aspects of this development are significant.
The environmental and social costs for this pattern of development are significant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com