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The block to development was prevented by co-injection of c-Fyn mRNA with the dominant-negative construct indicating that it was a specific effect.
On 29 March, a low-level circulation was visible, though significant tropical development was prevented due to wind shear and land interaction with islands in the Indonesian archipelago.
This development was prevented by the treatment of mice with either the mTOR inhibitor rapamycin or the MEK1/2 inhibitor (PD0325901).
Seizure development was prevented in most animals, and if present, they only lasted for a maximum of 15 min (Fig. 5b).
Although it was discovered in the 1970s, its clinical development was prevented by failure to devise a suitable formulation for this compound and the unpredictable and severe toxicity observed in early clinical trials, in particular myelosuppression, gastrointestinal toxicity, and haemorrhagic cystitis (Gottlieb et al, 1970; Muggia et al, 1972).
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Native SS14 binds with nanomolar affinity to all five human receptor subtypes, hsst1-5, but its use for drug development is prevented by its poor in vivo stability [8].
Since the Iraqi-Iranian War in 1980s and the First Gulf War in 1991, followed by the international sanctions, investment in new infrastructure and planning development were prevented.
In such cases, the connections must be capable of resisting the combined axial and flexural loads and allow for the redistribution of the loads, so that progressive collapse development is prevented.
When F-actin polymerization is inhibited, completion of oocyte meiotic maturation and embryo development are prevented [16].
Elsewhere in New Jersey the office market is strong, but the obstacles to development are preventing any hint of overbuilding, said Donald Eisen, the director of the suburban operations of Cushman & Wakefield.
Long term developments are prevented by a number of barriers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com