Sentence examples for development was discontinued from inspiring English sources

Various components of the ABC were designed and built from 1939 to 1942, but development was discontinued with the onset of World War II.

Alas, it was vaporware, and despite great hue and cry from gadget bloggers (the most influential people on the planet), development was discontinued.

Early compounds were found to produce liver toxicity, however, and development was discontinued.

Leptomycin B (LMB) specifically binds and blocks CRM1 and potentially inhibits growth of various cancer cell lines, but its clinical development was discontinued due to significant toxicity (Newlands et al, 1996; Mutka et al, 2009; Pathria et al, 2012).

The beneficial effects of the drug may be partly lost in the aging brain (Bishay et al, 2013), and ultimately, its development was discontinued for Alzheimer's disease because efficacy in clinical phase III trials was insufficient (Green et al, 2009).

Vorozole is a third generation, aromatase-selective AI, that entered phase 3 clinical trials, but further development was discontinued when no improvement in median survival was obtained compared to megestrol acetate.[ 45] Nonetheless, we explored the feasibility of designing a DASI that is structurally related to vorozole.

It is not uncommon that some small molecules in clinical development are discontinued because of abnormal liver function as a non-target related side effect.

Development for AD was discontinued after phase I. AAB-003 is Fc-engineered bapineuzumab.

As a result of these observations, clinical development of bevirimat was discontinued in June 2010.

This drug showed modest efficacy [ 78], but nevertheless clinical development in RA was discontinued.

Because the clinical development of aplaviroc was discontinued due to hepatotoxicity, there remains concern that hepatotoxicity may be a CCR5 antagonist class effect (Anon. 2005d).