Thus, the development of TRAIL sensitizers is needed to increase sensitivity against TRAIL.
In addition, there are plans for stables that will offer horseback riding on trails throughout the development; the trails, 20 miles in all, will also be used for hiking and biking.
Unfortunately, the clinical development of TRAIL was hampered, and could be attributed to its instability, bioavailability or poor delivery.
No roads, motorized vehicles (except rescue helicopters and other emergency vehicles), or any development beyond trail maintenance are allowed in this area.
However, in myeloid leukemia, development of TRAIL resistance is a major bottleneck limiting therapeutic efficacy.
And also because, as the jargon concept du jour, it leaves other development theories trailing in its wake.
A fishing creek runs through the development, and trails for hiking and biking are nearby, as is Yosemite National Park and other recreation areas.
This exciting discovery provided the basis for the development of TRAIL-receptor agonists (TRAs), which have demonstrated robust anticancer activity in a number of preclinical studies.
In one of the few major developments not trailed before the energy bill was finally published today, producers of steel, cement and chemicals will be among a string of electricity-intensive companies who will not be asked to contribute to the cost of a key subsidy designed to encourage investment in nuclear, wind, solar and other forms of renewable energy.
The development of the trail was supported by Highland's Rotary club, which has since built several utilities for trail users, including a pavilion, garden and parking lot.
