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Here we have used a combination of global gene expression and chromatin-immunoprecipitation approaches during the early stages of haematopoietic development to define the transcriptional programme controlled by Runx1, an essential regulator of blood cell specification.
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These tools are used for the system development to define and evaluate core application technologies.
We also previously used this model of in vitro pancreatic development to define signals and conditions that modulate the differentiation of PDX1-positive pancreatic progenitors into NEUROG3-positive endocrine progenitors.
It was decided early in development to define separate "View" and "Draw" modes.
Studies on corrosion barrier development allowed to define the required Al content for the formation of thin alumina scales in LBE.
More research is needed to formally examine the reproducibility of the methods of assessing systems development, and to define the cause-effect relationship between healthcare systems and quality of diabetes care using longitudinal study designs.
To gain insight into ARX's role in brain development we sought to define the downstream targets of ARX in the developing brain.
The issue of numerical uncertainty addresses the development of methods to define the magnitude of error or to bound the error in a given simulation.
Programmers can use the full potential of Java's GUI development interface (SWING) to define the look-and-feel and interaction between the user, NASA World Wind classes and custom modules.
Our results show that both the development of methods to define the TCs and of protocols to enhance assessment of ENM release from nano-applications will contribute to increase the exploitability of the data provided for MFA models.
We therefore performed an immunolocalisation assay at consecutive stages of pre-implantation development in order to define the localisation pattern of aPKC in the PrE.
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