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The discovery in 1976 of natural gas reserves offshore and in the Nile delta spurred industrial development; the principal beneficiary was Al-Dukhaylah, which became a major iron and steel centre.
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The British Isles led the world in the development of the principal beef breeds; Herefords, Angus, beef Shorthorns, and Galloways all originated in either England or Scotland.
This paper discusses the work of the URSULA project at the University of Sheffield, in which a participative and integrative approach to urban river corridor development, incorporating the principal of sustainability was used.
But over the last couple of years, it has become a favored destination among seasoned travelers, partly because it is not yet overcrowded; partly because it has the most evocative (and best-run) fort museum in the region (Mehrangarh Fort, below, top); and partly for the exceptional shopping, which owes to the city's development as the principal Indian center for exports of handicrafts.
Under the new development paradigm, the principal responsibility for the continent's social and economic crises was laid at the doorstep of the state.
These conclusions address persistent issues regarding the specificity of the targeted ablation and the regulated development of the principal preplate neurons.
These results are fully consistent with the Gene Ontology analysis of the hdac1 mutant (Additional file 2), which identified genes involved in transcriptional control and developmental mechanisms, including nervous system development, as the principal targets of Hdac1-mediated transcriptional regulation.
During the early steps of development of the principal tumour types, such as colon, lung and prostate, but also liver tumours, a subset of these premalignant cells undergo subsequent irreversible genetic alterations that allow them to mediate tumour growth.
This group would convene regularly, over the course of the emergency investigation, to review the latest developments in the outbreak, and to ask themselves whether there were alternative interpretations of the data, or concurrent developments, that the principal investigating team had either missed or too readily dismissed.
Mr. Obama used the United Nations development conference to announce a plan to reinvigorate American development efforts and the principal agency for delivering them, the United States Agency for International Development, which languished for years with financing cutbacks and a loss of talented employees.
For some of the boys, "their social and emotional development is not at the same level as their intellectual development," said Donna Taylor, the principal of the Brooklyn School of Inquiry.
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