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With increasing fetal development, the mechanism of mammalian wound healing transitions from regeneration to a repair process characterized by organized wound contraction and scar synthesis.
We present recent findings related to the expression pattern of the protein during development, the mechanism of HMGN5 action on chromatin, and discuss the possible role of HMGN5 in pathological and physiological processes.
Although the work cited above provides convincing evidence that the DOCK180/Mbc-ELMO complex is essential in development, the mechanism by which at least five Rac-specific DOCK proteins bind to one or more ELMO proteins in vertebrates to modulate actin regulation in a tissue-specific manner is not clear.
Although several studies have demonstrated the role of phospholipid signalling in vascular growth and development, the mechanism is still unclear.
Although, these studies strongly suggest a role for Nck in cancer development, the mechanism by which Nck oncogenic potential is achieved still remains to be established.
The effects that fire retardants, incorporated into polymeric materials as a means of improving flammability characteristics, may have on smoke development, the mechanism of polymer degradation, and on the survival response of laboratory animals are also considered.
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Given the decisive role of neurogenin-3 in islet development, the mechanisms that control its expression in the developing pancreas thereby control the generation of islet cells.
While this evidence clearly indicates a role for MYCN during brain development, the mechanisms remain somewhat unclear.
Despite their essential roles in immunity, tumorigenesis, and development, the mechanisms of aGPCR activation and signal transduction have remained obscure to date.
To further investigate the role of Id3 in tissue and embryo development and the mechanism of Id3-mediated growth regulation, we generated and analyzed Id3-deficient mice.
DfID will work with the World Bank to support the development of the mechanism and train money-transfer operators in Somalia over the next 12 months.
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