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Potential reasons for differences in risk factors between the models include the size of the dataset available for model development, the availability of each risk factor, differences in the time interval of data collection, difference in the populations studied between development datasets and differences in risk factor definitions.
The stage of the IP's development, the availability of information and the aim of the valuation will influence the method used.
This is due to the availability of strategies to successfully engineer antibodies into humanized forms, better understanding of the biological processes involved in cancer development, the availability of novel recombinant antibody formats, better antibody selection platforms, and improved antibody conjugation methodologies.
Given this development, the availability of thoroughly phenotyped patient and control samples is becoming even more important.
At the first level the 'super ordinate level' Labonté locates two major categories of elements: the political, economic and civil society traditions underlying society and the level of economic development, the availability of environmental resources and of human resources.
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In addition, recent reports have shown that the prediction accuracy of QSAR models can be increased when additional information from cell based assays is utilized [3], [4] Independently to these developments, the availability of functional genomics technologies facilitated the measurement of mRNA concentrations, proteins and metabolites in single experiments.
While the F.D.A.'s approval is certainly a welcome development, improving the availability of abortion services for all women remains a significant challenge for the future.
A third development is the availability of on-line storage of large datasets, especially of open data, including GIS coverages and remotely-sensed images.
The main difficulty encountered during the METRONOME methodological development was the availability of project result (e.g. Final Report) data.
The key requirement for data-driven prognostics algorithm development is the availability of multivariate historical data about system behavior.
The ease of distinguishing the stages of dental development and the availability of panoramic radiographs are practical reasons for attempting to assess the physiologic maturity without resorting to hand-wrist or lateral cephalometric radiographs (Krailassiri et al. 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com