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This conclusion highlights the most vexing aspect of the antibiotic development shortage: how to simultaneously stimulate research and pay for R&D costs while ensuring affordability.
However, all of these firms failed because of an array of problems: lack of sustained public or private investment in research and development, shortage of cassava roots, fragmented market for cassava products, unacceptable consumer taste and high cost of labour for hand peeling.
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While some teacher mobility is normal and expected, high turnover rates can produce a range of organizational problems at schools, such as discontinuity in professional development, shortages in key subjects, and loss of teacher leadership.
Some trigger-happy, bear-fearing people have preemptively shot bears, and in 2010, Grizzly bear deaths reached near record levels, in part because of the bears being increasingly pushed into inhabited areas due to expanding human development and shortage of food sources possibly resulting from climate change.
But with further economic development, food shortage is no longer a common problem in a society [ 32].
Nutrients of interest in the nutritional depletion hypothesis have to meet several criteria: (1) they have to be necessary in pregnancy and fetal development, with shortage leading to an adverse pregnancy outcome; (2) their maternal functional status should decline during pregnancy; and (3) their normalisation to a sufficient concentration after pregnancy has to be slow.
Local citrus cultivation is besieged by development, water shortages and the threat of greening disease, but Robert Knight Jr., who accompanies him to the market, is trying to support local farms through a community-supported agriculture program, the Inland Orange Conservancy.
Besides bird predation and water quality deterioration caused by pollution, which are likely to impose further constraints on the expansion of existing mussel farming operations, two main problems for the mussel industry can be linked closely to its future development: seed shortages and biotoxins that lead to long-term industry closures.
In addition to a few rounds of cooling measures, which included raising transaction tax and stamp duties, Leung has sought to seek land in the new territories and country parks for development, citing a shortage of developable land.
And the unreasonable electricity pricing caused by cross subsidization has become increasingly serious with the economic development and energy shortage.
Mr. Bush's 10-year, $7.1 billion energy policy focuses mainly on oil and gas development, not the shortage of power generation and bottlenecks in distribution that have contributed to the California crisis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com