This was in line with his epigenetic idea basic to embryology ever since that development proceeds from simple to complex, from homogeneous to heterogeneous.
Nevertheless, nowadays, the essential advancement in structural design development proceeds from progressive transition, away from the deterministic understanding of structural system behavior,, towards the statistic and probabilistic approaches to structural reliability, considering the random distribution of action and resistance characteristics.
As development proceeds, from ED11.5 to adult mouse, liver cells exhibited the change of cell shape from spindle to polygon, with larger size and tighter intercellular connections (Figure 1A).
Larval development proceeded from 96 h post fertilization to the eyed veliger and pediveliger stages (i.e., achieved competence) among the largest size classes in all treatments and across all experiments.
Collectively, these observations suggest that c-Kit expression during HSC development proceeds from low to high but is lost in committed haematopoietic progenitors.
At the time of ZGA, development proceeds from a control by mRNAs synthesized during oogenesis and stored in the egg (maternal transcripts) to mRNAs produced by the embryo's own genome.
The number of CD11c+ DCs was consistently increased (especially outside the perivascular area) in the three cases in which the lesion development proceeded from d0 to d14 (Figs. 1n p, 2).
When this information is combined with our observation that turtle orthologs exhibited increased mRNA accumulation as development proceeded from stage 14 to stage 17 (early in TSP) it is reasonable to speculate that these genes play a role in turtle development, potentially sexual development in the case of MMP2.
Epidermal development proceeds from a single layer of multipotent surface epithelial cells during mid-gestation, to a stratified epidermis consisting of multiple cell types at birth, and finally to a continually self-renewing homeostasis in the mature adult epidermis [ 66- 68].
We used a non-ortholog based strategy and identified four genes that exhibited increased mRNA expression as development proceeded from stage 14 to stage 17, a set of genes that responded to E2 exposure, and two genes (MALAT1 and C16ORF62) that show greater accumulation at the male producing temperature than at the female producing temperature.
