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Overall, the initial clinical validation step in our biomarker development procedure has allowed us to answer two critical questions for the potential applicability of the biomarker in clinical practice; hence, in our opinion, this step is essential for fast streamlining of the biomarker validation process.
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Details of the development procedure have been described in a previous paper [ 44].
The quality of the guideline (e.g. strength of evidence) and the guideline development procedure have also been identified as key factors for increasing guideline credibility and usage [ 3, 26].
Currently, most product development procedures have been characterized as unnecessarily complicated.
This approach requires substantial validation and development, yet we predict that the procedure has enough sensitivity to be used on small blood volumes.
This procedure has been fully described for the original development of the ADDQoL for adults [ 8].
The procedure has certain risks.
This procedure has completely changed my life.
This procedure has many advantages.
This procedure has 5% superfat.
The development of optimization design procedures has emerged as an essential component primarily to overcome the challenge of high initial construction costs associated with the fiber reinforced polymer (FRP) bridge deck systems.
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