Previous published descriptions of trichome development mention outgrowth, extension growth and branching.
Similar to vertebrate limb development, the outgrowth of both the pectoral and median fins is maintained by an epithelial structure – the apical ectodermal ridge (AER).
Identical phenotypes, namely an arrest of mammary gland development before outgrowth of the primary sprout, occur upon targeted deletion of PTHrP or the receptor PTHR1 [ 14].
The current view of tumor heterogeneity recognizes basic principles of Darwinian evolution at the core of neoplastic development and outgrowth: a single somatic cell with a heritable fitness-promoting mutation proliferates, conferring a survival advantage that allows cells to outlast the less 'fit' cells [ 3, 4].
Shoot primordia were dissected from axillary buds from the second, third and fourth node distal to the most distal fruit and represented the same developmental unit, starting as latent buds established during the first season that were dormant over the winter months and resumed development and outgrowth in the spring.
Furthermore, the proliferation and development of outgrowths from these cells is increased by pregnancy.
The ongoing accumulation of additional mutations also contributes to the growth of local tumor cells, the development of metastatic outgrowths, and the emergence of therapy resistance.
Community development corporations, an outgrowth of Great Society legislation in the 1960's, were nonprofit organizations financed by the government that provided housing and social services in low-income neighborhoods.
This correlates with altered morphologies during the neuronal development, including axon outgrowth, guidance and conductivity.
Although the development and axon outgrowth of these motoneurons has been characterized, cues that determine whether axons will grow dorsally or ventrally have not been identified.
