However, the diagnosis of various heart diseases (e.g., angina pectoris, coronary artery disease) was difficult.
Some panels predict risks of various heart conditions.
The mitochondria play a critical role in maintaining the normal function of the heart, and therefore mitochondrial dysfunction is related to the pathogenesis and development of various types of heart disease [ 33].
Chronic exposure to iAs is associated with the development of various diseases including heart disease, diabetes, and cancer, and exposed individuals often present with hallmark skin lesions.
Obesity is a risk factor for development of various diseases including coronary heart disease, dyslipidaemia, hypertension, stroke, some forms of cancer, type 2 diabetes mellitus, gallbladder disease, osteoarthritis and gout, and pulmonary diseases, including sleep apnoea [ 2].
Mutation of Pax3 in Splotch mice perturbs the neural crest affecting development of various structures including the outflow septum of the heart [ 21, 22, 52].
In 1962, a report of a committee of the Royal College of Physicians in Great Britain declared, "cigarette smoking is a cause of lung cancer and bronchitis, and probably contributes to the development of coronary heart disease and various other less common diseases".
The original purpose of this study was to investigate the relative roles of various risk factors on the development of ischaemic heart disease.
