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The development of the trial in terms of design factors such as sample size estimates and the selection and randomization of communities to intervention or comparison is described.
Development of the trial protocol, design of the Radio Frequency (RF) coils and Quality Control procedures necessary to ensure that the datasets acquired at each centre were comparable, are described.
SA contributed to the development of the trial protocol.
Development of the trial was informed by earlier feasibility work.
RJD, JB and HWFE contributed to the development of the trial protocol.
All authors contributed to the design and development of the trial protocol.
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This Note provides an overview of the development of the trial-publicity rules, a glimpse of the media coverage of the Blagojevich trial, and a proposed rule to guide defense lawyers' extrajudicial advocacy.
All of the authors contributed to the design and development of this trial protocol.
We would like to thank M. Tanner (former director of the Swiss Tropical and Public Health Institute, Basel) for his vision and support of the development of the clinical trial platform enabling whole sporozoite based malaria vaccine trials in Bagamoyo, Tanzania.
The objective of this report is to describe the development of the AHEAD2 trial, including the methods, research infrastructure, and other features of the randomized clinical trial design.
The pilot study informed the development of the full trial protocol and achievement of competitive funding.
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CEO of Professional Science Editing for Scientists @ prosciediting.com