Three years ago, another team studying enhancers in the development of the mouse face and skull uncovered similar complexity.
During development of the mouse embryo, blood cells are generated from mesodermal precursors at specific times and locations.
Herein we test the hypothesis that the basement membrane protein laminin α5 (LAMA5) plays a key role in the development of the mouse genital tubercle, the embryonic anlage of the external genitalia.
To find that gene, developmental biologist Deepak Srivastava of the University of Texas Southwestern Medical Center at Dallas and colleagues studied development of the mouse heart, in which a transcription factor called dHAND was known to turn on an array of crucial genes.
The gradual and significant increase in MTA1/MTA1 expression was observed during postnatal development of the mouse epididymis.
Moreover, the most extensive staging classification for development of the mouse face is based on this strain [10].
The asymmetric cell divisions observed during pre-implantation development of the mouse embryo differ from these models since centrosomes are absent until the blastocyst stage [3].
Sanders and co-workers [18] argue that the lack of Vent gene in the mouse is due to slower development of the mouse embryo.
Elf5, an epithelial specific Ets transcription factor, plays a crucial role in the pregnancy-associated development of the mouse mammary gland.
We observed a dramatic reversal in the formation of CSPG-related structures across neostriatal compartments during early postnatal development of the mouse neostriatum.
Temporal expression analysis by GeneChip microarrays revealed low levels of PLD4 mRNA expression during postnatal development of the mouse cerebellum (Fig. 2).
