"Together with the Harbour Way link road, proposals for the development of the docks and the improvements to lower Station Road, the whole area will be most impressive.
Much of the growth of Portishead's population can be attributed to the development of the former docks into a vibrant community.
Both this and its successor the Southern Railway (UK) played a significant role in the creation of the modern port following their purchase and development of the town's docks.
A set of forty-seven Akt1 inhibitors was used for the development of molecular docking based QSAR model by using nonlinear regression.
Despite the advances in the development of docking approaches and scoring functions, the genome-wide application of many ligand docking/screening algorithms is limited by the quality of the binding sites in theoretical receptor models constructed by protein structure prediction.
A broad interest in compound docking brought about a significant progress in the development of docking algorithms with many tools currently available; for instance, AutoDock [31, 34], GOLD [35], Glide [30], rDOCK [36], Surflex-Dock [37], FlexX [38], FRED [39], and DOCK [40].
However, with the development of docking methods it is possible to globally sample the entire conformational space of two interacting proteins, generating all low energy states.
Tourism focused on the pre-Hispanic ruins has increased with the development of railroads, highways, docking facilities for cruise ships at Progreso, and an international airport at Mérida.
The development of docking software that is able to accurately predict binding geometry and binding energy represents a great challenge in computational chemistry [68, 71 73].
