Sentence examples for development of the definitive from inspiring English sources

Of interest are organs derived from the definitive endoderm, such as the pancreas and liver, and animal studies have revealed an essential role for Nodal in development of the definitive endoderm.

Apoptotic cells were observed in close spatial and temporal association with the invasion of peritruncal vessels into the aorta (HH 29-31), the initial formation of coronary orifices (HH 32-33), and the further development of the definitive coronary arteries and orifices (HH 34-35).

The primitive wave of blood cells formed normally in mutants, later, however, mutants lost these cells (Fig. 1G,H) and the development of the definitive wave of blood cells was suppressed as it was illustrated by the decreased number of cells expressing runx1, a marker for hematopoietic stem cells (Fig. 4F G).

The establishment of the maternal circulation is a progressive phenomenon that modulates the development of the definitive placenta.

All the remarks given by the experts were included in the development of the definitive competence inventory which was confirmed by the fourth and last Delphi round.

The future development of the definitive blood system correlates with the formation of the septum in the lophophoral vessel and its division into upper and lower portions (afferent and efferent lophophoral vessels) as well as with the formation of two lateral blood vessels, which are descendants of the ventral blood vessel.

We also suggest that the breast CSC population detected by CD44/CD24 or ALDH1 expression is heterogeneous and hence that validation of these CSC markers and the development of the more definitive markers would be important.

Principally, we focused on the morphological development of the endoderm into the definitive intestine, as well as on how the mesoderm segregates from the endoderm and its putative influence on the formation of the gut.

The need for a more detailed understanding of the development in the definitive host is underscored by the fact that infected cats shed hundreds of millions of oocysts that can remain infectious for over a year to a wide range of highly susceptible intermediate hosts, including humans [ 7].

The findings support the development of a definitive trial that embraces personalised recruitment strategies and the development of approaches to improve retention over a clinically relevant intervention period.

Having determined that isthmic function was likely to be unimpaired, we chose to examine the effect of ectopic Hoxa2 on the development of three definitive r1 neuronal populations: cerebellar granule cell precursors, trochlear motor neurons and the locus coeruleus.