Sentence examples for development of the combination from inspiring English sources

This approach led to the development of the combination index (CI) popularized by Chou and Talalay [18].

The development of the combination of LHT + UNSM treatment was successfully demonstrated the possibility of being applied to Ti-6Al-4V alloy to achieve a significant high hardness.

The co-formulated combination with artesunate, Lapdap-plus™, was under development, but because it was associated with an increased risk of anaemia GSK has stopped the further development of the combination therapy and commenced a product recall process at pharmacy level in Kenya for Lapdap™ the only market with recent sales of the product [20].

After establishing both oral vinorelbine and capecitabine as a standard of care in MBC, the development of the combination of both agents has a very strong rationale.

The decision tree neatly summarizes our experimental results, but ultimately may be useful to guide clinical development of the combination regimens.

11 The rationale for the development of the combination oxycodone naloxone (OXN-PR) was based on the fact that oral naloxone, due to its very low systemic bioavailability, predominantly antagonizes opioid receptors in the gastrointestinal tract, thereby preventing bowel dysfunction induced by oxycodone, without affecting the central, analgesic effects of oxycodone.

In this review, we explore the key considerations in the development of these combination drug delivery systems.

These results support the development of this combination for treatment of solid tumours.

To accelerate the preclinical development of these combination therapies, reliable single target validation is necessary, followed by the rational selection and systematic testing of combination approaches.

An important line of future development concerns the combination of S-layers with planar lipid membranes, liposomes, and emulsomes (Schuster & Sleytr, 2009b; Ferner-Ortner-Bleckmann et al., 2011; Ücisik et al., 2013b).

Disease progression was defined as the development of any combination of the aforementioned conditions, initiation of vasopressors, or death within 96 h of ED presentation.