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Scientists from Canada and the disease control centers have since cracked the genetic code of the virus that causes SARS, leading to the development of tests that can confirm infection.
Molecular diagnostics: development of tests that will determine mutated genes in a patient's tumour, tumour expressed molecules that can be targeted, and the overall mutational gene expression profiles that can predict a response to the treatment.
Thus, knowing the main biochemical contributors to resistance has not led to the development of tests that are predictive of tumour behaviour, nor has it led to substantive improvements in patient outcomes.
Despite the significant progress and development of tests that can discriminate BSE from scrapie in a single infection scenario, limited studies have been conducted that address the performance of the discriminatory tests in cases where BSE and scrapie exist in the same animal.
Simultaneously, we demonstrated inherent diversity among a number of SE isolates at many SNP loci and in their prophage content, paving the way for the development of tests that could be used to differentiate lineages and to subtype isolates of SE for the purpose of tracking through biological systems including foods, the environment and infected humans.
The new sperm diagnostic/selection technologies being developed are focussing more on the development of tests that both diagnose and select or deselect sperm on specific cellular characteristics.
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Implementation of the determination of these proteins requires development of immunoenzymatic tests that would be applicable on commonly used laboratory platforms for in vitro diagnostics, not only for scientific research.
One concern going forward is that a thicket of patents on individual genes will impede development of newer tests that look at multiple genes or of whole genome sequencing.
Recent innovations include development of diagnostic tests that could improve detection of the parasite.
Many issues must be prospectively considered in a methodical, systematic, and scientific fashion if progress is to be made in the development of validated tests that will have value in the management of patients with cancer.
Translation of these discoveries into clinical applications requires the development of genomic tests that can reliably detect such somatic alterations with high sensitivity and specificity.
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