Sentence examples for development of stimulant from inspiring English sources

Here, we have shown that impulsivity is likely to be a heritable risk factor predisposing to the development of stimulant dependence.

Indeed, sensation-seeking has been linked with the initiation of substance abuse, but impulsivity, rather than sensation-seeking, has been associated with the development of stimulant dependence (20).

Smoking may be one important stage or inducing factor for using illicit drugs and early exposure to nicotine may precipitate the development of stimulant addiction [ 8– 11].

It is therefore arguable that relatively low levels of sensation-seeking behavior in the siblings may have protected them from initial exposure to stimulant drugs and therefore counteracted the predisposing effects of high impulsivity on development of stimulant dependence.

For further results, see Supplement 1. Trait-impulsivity was not only increased in the drug users but also in their siblings, indicating that it could be an endophenotype or vulnerability trait predisposing to development of stimulant dependence.

Symptoms to diagnose stimulant dependence include the presence of physical and psychological damage, craving, reduced ability to control stimulant use, development of stimulant tolerance with increased dosage for stable stimulant effects, withdrawal symptoms in case of abstinence, and mentally focusing on stimulant use and continued use despite detrimental consequences of stimulant use.

The development of effective treatment for stimulant addiction historically has been difficult.

The risk of addiction development by stimulant use for NE is still unanswered.

The development of sensitization to psychomotor stimulants leads to enduring changes in neural function responsible for behavioral augmentation.

Amphetamine-induced increases in VTA DCC protein levels are prevented by co-administration of NMDA receptor antagonists [ 32], seems to lead to changes in synaptic plasticity, and is required for the development of behavioral sensitization to stimulants [ 25].

Future longitudinal studies using several imaging modalities will need to assess the fundamental question of the impact of stimulant medication on the development of brain structure, function, and biochemistry of ADHD children.