The development of specific positions, such as Knowledge Brokers (KBs) or contracts with external KBs who are responsible for building capacity and supporting the use of evidence among public health professionals, helps establish an organizational climate that is supportive of research use [ 20- 22].
However, these are complex pedagogical processes engaging diverse content areas (e.g., debates in international development, specific knowledge of training site, profession-specific knowledge) [ 29] and multiple forms of knowledge (e.g., factual, reflexive) [ 30, 31].
Prolonged antibiotic therapy is known to promote the adaptation of organisms and development of specific cross-resistance mechanisms although knowledge of the local resistance trends in ophthalmic specimens is mandatory to provide a prompt and effective treatment [ 27, 28].
They provide empirical data regarding what many have written about regarding barriers to evidence-based decision-making and research utilization [ 23, 34, 69- 71], they have implications for understanding how research evidence is taken-up and interpreted in policy and practice, and they can inform development of specific KT strategies in contested knowledge areas.
In addition, we look for the development of specific HIF-1 inhibitors; to our knowledge there are no reports of an effective HIF-1 inhibitor in animal models.
To be part of a network necessitates development of specific capabilities such as absorbing capacities, new knowledge in specific niches and relationship capabilities.
As Life Cycle Assessment has been increasingly explicitly required in R&D projects, efforts have been dedicated to enlarge knowledge on the development of specific tailored LCA methods and tools and on the application of LCA in inter-organizational R&D projects in general.
Given that unique core genes exist, the cellular processes these genes are involved in, can provide knowledge about niche adaptation and development of specific phenotypes.
This knowledge might then allow for the development of specific MMP inhibitors to prevent the gain of a metastatic phenotype in CRC.
In rare cancers, the knowledge of mutated kinases has led to the development of specific, potent small molecule inhibitors.
