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The ability to manipulate protein binding affinities is important for the development of proteins as biosensors, industrial reagents, and therapeutics.
Structure-based protein engineering coupled with chemical modifications (e.g., pegylation) is a powerful combination to significantly improve the development of proteins as therapeutic agents.
Following this progress, fusion protein technology, as a novel innovation, has opened new horizons for the development of proteins that do not naturally exist.
These results suggest that variability in the IxAC family is not due to the development of proteins specific for a development stage or a phase of the bloodmeal.
The evolution of protein sequences involves the changes, insertions, and deletions of single residue or peptide along with the entire development of proteins [ 48].
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Hodgkin, who was born in Egypt in 1910, was credited with the development of protein crystallography and established the structures of vitamin B12 and penicillin.
Citation: Chemist credited with the development of protein crystallography.
These observations might be helpful for the further development of protein polarisable force fields.
Pharmacokinetic analysis is essential for the research and development of protein therapeutic candidates.
"It was there that I broadened my experience of development of protein purification processes," she says.
Consequently, pharmacoproteomic-based drug discovery and development of protein therapies attracted a great deal of attention in recent years.
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