To obtain measurements of the DC electric field, which is thought to play an important role in the development of plasma outflow from the plasmasphere during magnetic storms, plume formation, and enhancement of injection processes of ring current particles.
It is also required in CNCC for development of the outflow tract (OFT) and ventricular myocardium [ 23].
The second heart field plays a critical role in the development of the cardiac outflow tract, and mutations in genes expressed in the second heart field result in outflow tract defects both in mouse models and in humans.
Development of left ventricular outflow tract obstruction (LVOTO) in patients with hypertrophic cardiomyopathy (HCM) is important for explaining symptoms and designing management.
Deletion of Fn1 using the Isl1Cre strain resulted in defective formation of the 4th pharyngeal arch arteries (PAAs), aberrant development of the cardiac outflow tract (OFT), and ventricular septum defects.
Secondly, the development of the cardiac outflow tract is initiated normally in GPR126 homozygotes.
Thickening and calcification of the aortic valve will lead to reduced opening and the development of left ventricular outflow obstruction, referred to as aortic stenosis.
Thickening and calcification of the aortic valve will lead to reduced opening and the development of left ventricular outflow obstruction, referred to as aortic valve stenosis.
To investigate the potential roles for ROCK signalling in the developing outflow tract, we carried out immunohistochemistry for Rock1 and Rock2 during key stages of outflow development between E9.5-E11.5.
While the FHF progenitors give rise to the left ventricle and the inflow tract (IFT), cells from the SHF (Isl1+) contribute to the development of the right ventricle, outflow tract (OFT) and parts of the IFT.
