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Considering that site-directed mutagenesis studies on DAT typically result in a decrease in DA uptake35,37,57,58, the enhancement of DA transporter as evidenced by the H547A mutant suggests that targeting this residue may provide an exciting knowledge basis for the development of novel concepts for the therapeutic treatment of the HAND.
Focusing research on cell-specific molecular biomarkers can help in the development of novel concepts for diagnosis and treatment of epithelial cancers.
Therefore, our findings encourage the further development of novel concepts for long-bone fracture fixation with variable stiffness, which might be used in the future to improve fracture healing and prevent or reduce nonunion.
Hence, the comparison of Bet v 1 with its non-allergenic structural homologues offers the possibility to shed light on such features, thus paving the way for a deeper understanding of the allergic sensitisation process and the development of novel concepts for prevention and treatment of allergy.
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With further research focusing on the development of novel sensing concepts and the reduction of sensor cost, the widespread use of optical sensors in concrete structures can become a reality in the future.
There is a great necessity for development of novel sensory concepts supportive of smart sensing capabilities in defense and homeland security applications for detection of chemical and biological threat agents.
His research interests have been in the area of basic biomedical research with particular emphasis on the immunological aspects of cancer as well as the development of novel therapeutic concepts for diseases with complement pathogenesis,based on the complement-depleting activity of cobra venom factor.
The development of this novel concept has been supported by the development of related technologies, as such as molecular design, molecular biology (genetic engineering) and cellular/tissular engineering.
Throughout the development of a novel concept for the treatment of converter dust in laboratory experiments, the fluidizing gas was changed during the operational start up from inert gas (N2) to reactive converter gas (CO, CO2 and N2).
This paper reports our experience in the development of a novel concept design support tool for cyber-physical systems (CPS).
The development of novel integrated reactor concepts should be in continuous dialog with reliable control and design models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com