The continuous search for new chemically diverse molecules and the development of new methods for culturing deep-sea microorganisms have placed the deep sea environment as a new frontier in the drug discovery process.
The work is diverse and is characterized by collaborations with biologically- and chemically-oriented scientists, the development of new instrumentation and techniques, especially as involves x-rays and synchrotron radiation.
These epitopes, defined at the peptide level, can be chemically synthesized and engineered for the development of new inexpensive and easier to perform assays and the improvement of the methods for autoantibody detection.
However, most of these plants, represent a virtually unlimited reservoir of molecules, are not explored chemically and can constitute lead molecules for development of new antimalarial drugs.
For example, her work in the synthesis of chemically modified cottons has been adopted for the development of new wood products and epoxy resins.
In fact, the glycoprotein has been quite often selected as a model compound in the development of new strategies for the structural analysis of N-glycosylation patterns, making use of chemically or enzymatically released carbohydrate chains from denatured material.
Chemotherapeutic bioassay for colorectal cancer (CRC) with a rat model bearing chemically-induced CRCs plays an important role in the development of new anti-tumor drugs and regimens.
In contrast, chemically defined synthetic or semisynthetic glycan sulfates may be rather promising for the development of new drug substances.
Triketones, derived chemically from a natural phytotoxin (leptospermone), are a good example of allelochemicals as lead molecules for the development of new herbicides.
Complex forming chemically modified silica are well known as efficient adsorbents are widely used in modern hybrid and combined methods of analytical chemistry, at the development of new treatment technologies.
